Caroline E Nunes-Xavier Selected Research

Everolimus

1/2022	B7-H4 Immune Checkpoint Protein Affects Viability and Targeted Therapy of Renal Cancer Cells.
1/2017	Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells.
2/2016	Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors.

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Caroline E Nunes-Xavier Research Topics

Disease

20	Neoplasms (Cancer) 01/2024 - 01/2012
5	Neuroblastoma 01/2023 - 12/2018
4	Renal Cell Carcinoma (Grawitz Tumor) 06/2023 - 01/2016
4	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2019
4	Breast Neoplasms (Breast Cancer) 02/2016 - 08/2010
3	Neoplasm Metastasis (Metastasis) 01/2018 - 01/2016
2	Kidney Neoplasms (Kidney Cancer) 01/2023 - 01/2022
2	Carcinoma (Carcinomatosis) 11/2021 - 01/2019
2	Melanoma (Melanoma, Malignant) 01/2019 - 01/2017
1	Carcinogenesis 01/2022
1	Medulloblastoma 01/2022
1	Osteosarcoma (Osteogenic Sarcoma) 01/2022
1	Adenocarcinoma 01/2021
1	Homocystinuria 04/2020
1	Methylmalonic acidemia 04/2020
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2019
1	Metabolic Diseases (Metabolic Disease) 01/2016
1	Lymphatic Metastasis 01/2016

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2012
6	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 01/2024 - 12/2013
5	Protein Tyrosine PhosphatasesIBA 01/2024 - 12/2013
5	Immune Checkpoint ProteinsIBA 01/2023 - 01/2020
5	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2016
3	Phosphotransferases (Kinase)IBA 06/2023 - 08/2010
3	Oxidoreductases (Dehydrogenase)IBA 06/2023 - 01/2022
3	Pyruvic Acid (Pyruvate)IBA 06/2023 - 01/2022
3	EnzymesIBA 01/2023 - 05/2014
3	Immune Checkpoint InhibitorsIBA 01/2023 - 01/2019
3	Everolimus FDA Link 01/2022 - 02/2016
2	Androgen Receptors (Androgen Receptor)IBA 01/2023 - 01/2021
2	MTOR InhibitorsIBA 01/2022 - 02/2016
2	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 12/2019 - 01/2019
2	Dacarbazine (DIC)FDA LinkGeneric 01/2019 - 01/2017
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019 - 08/2010
2	API 2IBA 01/2017 - 02/2016
2	Tyrosine (L-Tyrosine)FDA Link 12/2013 - 01/2012
1	Nonsense Codon (Nonsense Mutation)IBA 01/2024
1	major vault proteinIBA 01/2023
1	CateninsIBA 01/2022
1	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 01/2022
1	cabozantinibIBA 01/2022
1	lenvatinibIBA 01/2022
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Tyrosine Kinase InhibitorsIBA 01/2022
1	Axitinib (AG 013736)IBA 01/2022
1	temsirolimus FDA Link 01/2022
1	Prorenin ReceptorIBA 11/2021
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 04/2020
1	AntibodiesIBA 12/2019
1	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 12/2019
1	Dual-Specificity PhosphatasesIBA 03/2019
1	Phenobarbital (Luminal)FDA Link 01/2019
1	Cisplatin (Platino)FDA LinkGeneric 01/2019
1	EpitopesIBA 01/2019
1	PhosphotyrosineIBA 01/2019
1	p38 Mitogen-Activated Protein KinasesIBA 01/2019
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 12/2018
1	Monoclonal AntibodiesIBA 01/2017
1	VemurafenibIBA 01/2017
1	binimetinibIBA 01/2017
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2017
1	Peptide Hydrolases (Proteases)FDA Link 01/2016
1	Serine (L-Serine)FDA Link 01/2016
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 12/2013
1	ErbB Receptors (EGF Receptor)IBA 01/2012
1	Class 4 Receptor-Like Protein Tyrosine PhosphatasesIBA 01/2012
1	phorbolIBA 08/2010
1	Phorbol EstersIBA 08/2010

Therapy/Procedure

11	Therapeutics 01/2023 - 12/2013
3	Immunotherapy 01/2023 - 01/2020
2	Drug Therapy (Chemotherapy) 01/2019 - 01/2017
1	Aftercare (After-Treatment) 01/2022
1	Prostatectomy (Retropubic Prostatectomy) 01/2021
1	Lymph Node Excision (Lymph Node Dissection) 01/2019
1	Cystectomy 01/2019